KinDRed Skin - Treatments - Polynucleotides
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Polynucleotides

The break-through skin regenerative treatment that is taking the beauty and aesthetics world by storm.

about Polynucleotide treatment

Polynucloeotides are an exciting development in regenerative aesthetics.

Polynucleotides are derived from fish DNA and act as a powerful biostimulator in our skin. Essentially, they signal the skin cells to work harder to make more collagen and elastin.

The treatment involves multiple superfical injections of the gel with a very fine needle.

The benefits of the treatment are increased skin quality, elasticity, reduced fine lines, improved hydration and improved protection from free-radical damage.

The treatment can be used on the face, neck, body, hands and hair.

KinDRed Skin - Treatments - Polynucleotides

Your treatment will start with a skin cleanse and then application of a skin numbing cream.

Polynucleotides are injected into the superficial layers of the skin using a fine needle or fine cannula.

The treatment can feel a little stingy during injection but this is only momentary.

After the treatment, you will notice little bumps and some puffiness around the treated area, but these will go down.

Polynucleotides come in 2ml syringes so we normally use them treat a specific area at a time. There are specific polynucleotide products that treat certain areas and concerns.

Philart Eye –  especially formulated for use around the eye area to treat abnormal pigmentation, dark circles, crepey skin and general signs of periorbital eye aging.

Philart – formulated for general use. We have had good results with this to treat forehead lines. It can also be used to stimulate hormonal hair loss in the scalp and eyebrows.

Philart Next – this product is a powerful mixture of hyaluronic acid and polynucleotides. We have had great results with using this in the mid face (cheeks), neck and upper lip lines.

45 minutes

Small “bumps” will be visible under the skin. They usually last between 4 – 48 hours. There may be minor bruising. You can return to normal activities after a treatment.

Polynucleotides help to improve skin hydration so you may see an immediate improvement in fine lines. The main results rely on your own skin cells to start working harder and more effectively. This can take time so expect to see full results after 6 months. Skin will remain improved for months to years.

Polynucleotides are relatively new to aesthetic medicine but have been used for several years in burns therapy with a good safety profile. They are injected into the superficial layers of the skin so we avoid risk to deeper structures.

Risks include small bruises, a theoretical risk of infection (we take great care to reduce infection risk), and allergy. Philart has extensive clinical date with excellent safety record.   

After your treatment, you should avoid touching the treated area or applying make up for 4 hours. You can use your usual skincare after this.

treatment areas

kinDRed Treatment - Polynucleotides

Polynucleotides can be used on the face, neck, body, hands and hair

Fine lines and wrinkles and crepey skin

Forehead lines

Neck area

Upper lip lines

Skin laxity on the face and neck

Dehydrated and dull skin

Aging and dark circles around the eye area

Hair loss in the scalp and eyebrows

Results

“I have recently started going to Hannah and couldn’t recommend her more, she takes the time to really understand your concerns and fully explains everything, without rushing or pressurising you. Her recommended treatments have been holistic in approach, the polynucleotides have been transformative, the skin quality around my eyes has noticeably improved.”

faqs

What can polynucleotides treat?

Polynucleotides are perfect for you if you want to focus on natural skin health and regeneration. Polynucleotides help with the following concerns:

Aging and dark circles around the eye area

Fine lines and wrinkles and crepey skin

Hormonal hair loss

Dehydrated and dull skin

Skin laxity on the face and neck

Are polynucleotides the same as filler?

No. Polynucleotides help to improve skin quality, hydration and health. They do not provide structure, support or volume like dermal fillers. Polynucleotides can be combined with dermal fillers and botulinum toxin for amazing results but are also a powerful stand-alone treatment.

Is there anyone that shouldn’t have polynucleotide treatment?

You should avoid polynucleotide treatment if you have a fish allergy or active infection/skin cancer/open wounds in the treatment area. The treatment would not be suitable for vegans.

What are polynucleotides?

Polynucleotides are derived from fish DNA (specifically salmon or trout sperm) that has been highly purified in the laboratory to give us chains of nucleotides.

How do polynucleotides work?

Polynucleotides act as a “bio-stimulator”. Once injected and absorbed into the skin, the polynucleotides act by stimulating fibroblast cells (to produce more hyaluronic acid, elastin and collagen), act as free radical scavengers (protecting cells from damage) and also have a direct hydrating effect. They may also have a stimulatory effect in adipose tissue which can help in certain areas of the face that has lost fat (eg. under the eye and the top lip).

Can I combine polynucleotides with other treatments?

Dr Hannah has developed a signature treatment which involves a combination of SkinPen microneedling with polynucleotides in a single treatment sitting. These powerful biostimulating treatments work synergistically to give amazing results. It also has the benefit that any minor downtime is combined.

There is evidence emerging that polynucleotides can work synergistically with botulinum toxin. The theory is that collagen remodelling of static lines (achieved by polynucleotides) is more efficient while the muscle is in a relaxed state.

However, you can still achieve great results with polynucleotide treatment alone.

Are polynucleotides better than Profhilo?

You can learn more about Profhilo here.

Polynucleotides and Profhilo can both be considered “skin boosters” as they will both increase the hydration of the skin and increase collagen production. However, there are important differences in these products.  Polynucleotides mainly work by being a powerful biostimulator. Profhilo mainly works by having a high concentration of hyaluronic acid and therefore giving a surge of moisture to the skin. Polynucleotides have the advantage of being able to be used in almost any area of the face whereas Profhilo is restricted to the mid/lower face and neck. Polynucleotides often take months to see full results, whereas Profhilo can give you a more rapid glow.

So, in summary, if your main concern is your forehead lines or under eye skin, you want to invest in the quality of your skin long term, and/or you have more mature skin then go for polynucleotides.

If you want a quick glow and plumpness to your skin on the cheeks/jawline and chin, such as before a holiday/wedding/event then Profhilo is the gold standard for this.

If you aren’t sure, that’s what a detailed consultation is for! Dr Hannah will assess your skin, explain the different products and make a recommendation for you.

What brand of polynucleotide do you use?

I use Philart brand. I selected this brand because it uses farmed trout which means they have been reared in controlled conditions (as opposed to wild fish). The fish used in the production of Philart go on to human consumption and therefore not wasted,

Does polynucleotide treatment hurt?

A strong numbing cream is applied before treatment. Most people find polynucleotides a bit stingy during each injection but this is momentary and not prolonged.

Why choose kinDRed skin for your polynucleotide treatment?

Dr Hannah was one of the first doctors to offer polynucleotides in Bristol and Cornwall. She started working with them in early 2023 (before many of the bigger clinics caught on!). Dr Hannah has performed a large number of polynucleotide treatments to date and this has allowed her to develop techniques to get the best results for her patients.

How many treatments do I need?

Some people notice a difference with a single treatment. However, we would advise an initial course of 3 treatments followed by a single booster treatment every 4-6 months.

How much does polynucleotide treatment cost?

Prices from £250 (see here for full pricing)  

Book your Polynucloeotides treatment